Skip to most important material Thanks for going to nature.com. You're utilizing a browser Edition with constrained aid for CSS. To acquire the top experience, we endorse you employ a far more current browser (or turn off compatibility mode in World wide web Explorer).Conolidine belongs to a bigger class of normal items, referred to as C5-nor stemm
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The very first asymmetric overall synthesis of conolidine was made by Micalizio and coworkers in 2011.[two] This synthetic route makes it possible for entry to both enantiomer (mirror image) of conolidine by means of an early enzymatic resolution."We confirmed that conolidine binds on the recently identified opioid receptor ACKR3, although showing